Donatella Donatelli, Corrado Mascia|||Foreword to the special issue on "Attempts of a mathematical uprising for restructuring biomedical sciences''|||159-163||| Alessandro Giuliani|||The actual status of quantitative approaches in Biology: problems and perspectives.|||165-176||| Maël Montévil|||Which first principles for mathematical modelling in biology?|||177-189||| W. Duncan Martinson, Helen M. Byrne, Philip K. Maini|||Multiscale modeling and simulation of traveling waves in biology: a review.|||191-216||| Isai Padilla and Ramón G. Plaza|||On the role of cancer cells' diffusion in the tumor growth paradox.|||217-231||| Donato Pera, Carlos Málaga, Chiara Simeoni and Ramón G. Plaza|||On the efficient numerical simulation of heterogeneous anisotropic diffusion models for tumor invasion using GPUs.|||233-255||| Pierfrancesco Moschetta, Chiara Simeoni|||Numerical investigation of the Gatenby-Gawlinski model for acid-mediated tumour invasion|||257-287||| Licia Romagnoli|||Numerical simulations of different models describing cerebrospinal fluid dynamics|||289-316|||